• What is VH IVUS?
  • VH IVUS Publications
  • IBIS II Study
  • Culprit of the Culprit
  • About Volcano Corporation

PROSPECT (Providing Regional Observations to Study Predictors of Events in the Coronary Tree) was the first prospective, international, multicenter, natural history study using 3-vessel multimodality intracoronary imaging to quantify the clinical event rate due to atherosclerotic progression and to identify those lesions which place patients at risk for unexpected adverse cardiovascular events. This landmark study of 700 Acute Coronary Syndrome (ACS) patients was co-funded by Volcano and utilized Volcano's proprietary VH® IVUS technology to classify lesions by plaque type. Three-year clinical event data was presented by Dr. Gregg Stone of Columbia University Medical Center on September 24, 2009 at the Transcatheter Cardiovascular Therapeutics (TCT) conference in San Francisco, CA.

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VH IVUS Lesion Assessment

What is VH IVUS?

Previously, assessment of atherosclerotic disease was limited to 2D views of symptom-causing narrowing of the coronary arteries by way of contrast agent-enhanced X-Ray imaging. More recently, grayscale IVUS allowed for quantification of atherosclerotic plaque build-up, in addition to providing precise measurements of vessel anatomy to guide optimal angioplasty or stent-based treatment.

Volcano's VH IVUS technology uses advanced spectral analysis techniques to allow simplified interpretation of ultrasound images and provide detailed information on the composition of each patient's atherosclerotic plaques. The colorized VH images show four plaque component types: fibrous, fibro-fatty, dense calcium, and necrotic core. VH IVUS images are created using Volcano's imaging systems along with the Eagle Eye® Gold IVUS imaging catheter.

Images are displayed live, in the cath lab for easy review by the interventional cardiologist and his or her staff while the patient remains on the table. No changes to standard clinical practice are required to employ VH IVUS. This novel technology provides automated measurement tools to simplify image interpretation and employs a pre-determined color key to display plaque composition at a specific point in the artery or across a region of interest.