PROSPECT (Providing Regional Observations to Study Predictors of Events in the Coronary Tree) was the first prospective, international, multicenter, natural history study using 3-vessel multimodality intracoronary imaging to quantify the clinical event rate due to atherosclerotic progression and to identify those lesions which place patients at risk for unexpected adverse cardiovascular events. This landmark study of 700 Acute Coronary Syndrome (ACS) patients was co-funded by Volcano and utilized Volcano's proprietary VH® IVUS technology to classify lesions by plaque type. Three-year clinical event data was presented by Dr. Gregg Stone of Columbia University Medical Center on September 24, 2009 at the Transcatheter Cardiovascular Therapeutics (TCT) conference in San Francisco, CA.

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VH IVUS Lesion Assessment

VH® IVUS Publications

Book Chapters



Topic Year Publication Link
VH 2007 Vince, D. G. and Nair, A. "IVUS Based Plaque Characterization". Editor, Virmani, Renu, Vulnerable Atherosclerotic Plaque. In press, 2007. Listing
IVUS 2006 Nair, A., Margolis, M. P., Davies, S. C. Vince, D. G.. "Intravascular Ultrasound". Mastering Endovascular Interventions; A Guide to Excellence. Lippincott Williams & Wilkins, 2006. Google Books Link
Plaque characterization 2005 Nair, A., Klingensmith, J. D. and Vince, D. G.. "Real-Time Plaque Characterization and Visualization with Spectral Analysis of Intravascular Ultrasound Data." Editors, Suri, Jasjit and Wilson, David L. Plaque Imaging. International Federation for Medical and Biological Engineering. Amsterdam IOS Press, 2005, v113: 300-320. Abstract
VH 2003 Vince, D. G., Nair, A., Klingensmith, J. D.,Margolis, M. P.,Burgess, Vi. "Radiofrequency Tissue Characterization and Virtural Histology." Editors, Waksman, Ron and Serruys, Patrick. Handbook of the Vulnerable Plaque. Martin Dunitz Limited, London, 2003. Google Books Link

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