• What is VH IVUS?
  • VH IVUS Publications
  • IBIS II Study
  • Culprit of the Culprit
  • About Volcano Corporation

PROSPECT (Providing Regional Observations to Study Predictors of Events in the Coronary Tree) was the first prospective, international, multicenter, natural history study using 3-vessel multimodality intracoronary imaging to quantify the clinical event rate due to atherosclerotic progression and to identify those lesions which place patients at risk for unexpected adverse cardiovascular events. This landmark study of 700 Acute Coronary Syndrome (ACS) patients was co-funded by Volcano and utilized Volcano's proprietary VH® IVUS technology to classify lesions by plaque type. Three-year clinical event data was presented by Dr. Gregg Stone of Columbia University Medical Center on September 24, 2009 at the Transcatheter Cardiovascular Therapeutics (TCT) conference in San Francisco, CA.

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VH IVUS Lesion Assessment

Culprit of the Culprit

The Culprit of the Culprit is an emerging clinical application where VH® IVUS has the potential to help improve the technical success of treating culprit lesions in acute patients, especially STEMI. Because plaque rupture sites that lead to clinical events are often found proximal to the luminal narrowing, they can be missed up to 60% of the time if relying on angiography alone, resulting in stent edges landing in or completely missing necrotic core. VH IVUS can identify the necrotic core and plaque burden typical of ruptured atheromas responsible for thrombotic events.

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