PROSPECT (Providing Regional Observations to Study Predictors of Events in the Coronary Tree) was the first prospective, international, multicenter, natural history study using 3-vessel multimodality intracoronary imaging to quantify the clinical event rate due to atherosclerotic progression and to identify those lesions which place patients at risk for unexpected adverse cardiovascular events. This landmark study of 700 Acute Coronary Syndrome (ACS) patients was co-funded by Volcano and utilized Volcano's proprietary VH® IVUS technology to classify lesions by plaque type. Three-year clinical event data was presented by Dr. Gregg Stone of Columbia University Medical Center on September 24, 2009 at the Transcatheter Cardiovascular Therapeutics (TCT) conference in San Francisco, CA.

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VH IVUS Lesion Assessment

VH® IVUS Publications

Editorials



Topic Year Publication Link
Plaque composition: CTA 2008 Voros, Szilard. "Can Computed Tomography Angiography of the Coronary Arteries Characterize Atherosclerotic Plaque Composition?: Is the CAT (Scan) Out of the Bag?" Journal of Americal College of Cardiology: Cardiovascular Interventions 2008, 1183-185, doi: 10.1016,j.jcin.2008.02.002. Abstract
Vulnerable Plaque 2007 Frutkin, Mehta, McGrary, Marso, S. Letter. "Limitation to the use of virtual histology intravascular ultrasound to detect vulnerable plaque". European Heart Journal 2007 ,doi:10.1093/eurheartj/ehm145. PDF
VH Value 2007 Nakazawa, G., Finn, A., Virmani, R. Editorial. "Virtual Histology: does it add anything?" Heart 2007; 93: 897-898. Abstract
Animal Models 2007 Virmani, R., Nakazawa, G. . Letter. Animal Models and Virtual Histology. Arteriosclerosis, Thrombosis and Vascular Biology 7 (2007):1666. Abstract
Plaque Morphology 2006 Burke, A., Joner, M., Virmani, R. Editorial. "IVUS-VH: a predictor of plaque morphology?" European Heart Journal 27 (2006) 1889-1889. PDF
Vulnerable Plaque 2006 Saunamäki, K. I. Editorial. "Virtual histology and the hunt for the vulnerable plaque" European Heart Journal 23 Nov. 2006. PDF

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