PROSPECT (Providing Regional Observations to Study Predictors of Events in the Coronary Tree) was the first prospective, international, multicenter, natural history study using 3-vessel multimodality intracoronary imaging to quantify the clinical event rate due to atherosclerotic progression and to identify those lesions which place patients at risk for unexpected adverse cardiovascular events. This landmark study of 700 Acute Coronary Syndrome (ACS) patients was co-funded by Volcano and utilized Volcano's proprietary VH® IVUS technology to classify lesions by plaque type. Three-year clinical event data was presented by Dr. Gregg Stone of Columbia University Medical Center on September 24, 2009 at the Transcatheter Cardiovascular Therapeutics (TCT) conference in San Francisco, CA.

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VH IVUS Lesion Assessment

VH® IVUS Publications

Reviews



Topic Year Publication Link
VH 2007 König, A., Klauss, V. Rev. of; "Virtual Histology". Heart Online 93 (2007): 977-982. Abstract
Vulnerable Plaque 2007 Mehta, S.K., McCrary, J. R. ,Frutkin, A. D., Dolla, W.J.S., Marso, S. P. Rev, of "Intravascular ultrasound radiofrequency analysis of coronary atherosclerosis: an emerging technology for the assessment of vulnerable plaque". European Heart Journal: 10.(2007):1093/eurheartj/ehm112. Abstract
Vulnerable Plaque 2007 Sangiorgi, G.M., Clementi, F., Cola, C., Biondi-Zoccai, G. Rev. of: "Plaque Vulnerability and Related Coronary Event Prediction by Intravascular Ultrasound With Virtual Histology: "It's a Long Way to Tipperary"?" Cardiovascular Credentialing International 70 (2007):203-210. Abstract
VH & Heart Transplants 2007 König, A., Sohn, H.Y., Rieber, J., Schiele, T., Killian, E., Klauss, V. "Coronary plaque classification using intravascular ultrasound - radiofrequency analysis in a heart transplant patient with severe atherosclerosis" The Journal of Heart and Lung Transplantation 26.9 (2007):960-961. Abstract
Event Prediction 2006 Sangiorgi, G., Clementi, F., Cola ,C. Rev. of; "Plaque Vulnerability and Related Coronary Event Prediction by Virtual Histology". Journal of Interventional Cardiology (2006);17-19. Article
Peripherals 2006 Wholey, M. H. Review; Endovascular Today August, 2006. PDF
Vulnerable Plaque 2005 Rodriguez-Granillo, G. A., Regar, E., Schaar, J., Serruys, P.W. Rev. of, "New Insights Towards Catheter-Based Identification of Vulnerable Plaque. Rev Esp Cardiol 58.10 (2005) 1197-206. Abstract
Autoborders 2003 Klingensmith, J. D., Schoenhagen, P. "Automated Three-Dimensional Assessment of Coronary Artery Anatomy Using Intravascular Ultrasound" (Review). American Heart Journal 145.5 (2003): 795-805. Abstract

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